What are lymphoid follicles?

What are lymphoid follicles?

Lymphoid follicles are small masses of tissues that contain aggregations of inflammatory cells, mainly B cells with some T cells and dendritic cells.

Where are lymphoid follicles?

Lymphoid follicles are 2–3 mm nodular elevations which are scattered throughout the small intestine but are found in highest concentrations in the distal ileum (Figure 7.13). They are more prominent during childhood and adolescence but may be seen at all ages and should not be mistaken for polyps.

What cells are found in lymphoid follicles?

Secondary follicles: lymphoid follicles with a germinal centre. These mostly contain B-cells. The nodes are covered by a capsule of dense connective tissue, and have capsular extensions, of connective tissue, called the trabeculae, which provide support for blood vessels entering into the nodes.

What are the 3 important lymphoid organs?

Lymphoid organs

  • Primary lymphoid organs: These organs include the bone marrow and the thymus.
  • Secondary lymphoid organs: These organs include the lymph nodes, the spleen, the tonsils and certain tissue in various mucous membrane layers in the body (for instance in the bowel).

What do lymphoid follicles produce?

Mature lymphoid follicles may contain high endothelial venules (HEV), follicular dendritic cells (FDC) and germinal centres with the potential to produce plasma cells and antibody responses against bacteria and/or auto-antigens, such as breakdown fragments from the extracellular matrix (ECM).

What is another name for lymphatic follicle?

The localized concentrations of lymphocytes that are seen in the respiratory tract, genitourinary tract, and gastrointestinal tract are lymph follicles. They are also called lymphatic nodules.

What is the function of lymphoid follicle?

Abstract. Primary lymphoid follicles (PLFs) in secondary lymphoid tissue (SLT) of mammals are the backbone for the formation of follicular dendritic cell (FDC) networks. These are important for germinal center reactions during which affinity maturation creates optimized antibodies in adaptive immune responses.

Which function of lymphocytes occur in lymphoid organs?

When naïve lymphocytes first encounter antigen in the secondary lymphoid tissues, they mount a primary immune response, generating both effector and memory cells.

What is the most important role of the lymphoid organs?

Since the function of the lymphoid organs is to filter and trap invading pathogens and present them to immune competent cells, the high levels of viremia seen following primary infection presumably lead to an efficient infection of the lymphoid tissue with HIV or SIV.

What is the body’s largest lymphatic organ?

Spleen: This largest lymphatic organ is located on your left side under your ribs and above your stomach. The spleen filters and stores blood and produces white blood cells that fight infection or disease.

What is the function of the primary follicle?

The primary role of the follicle is oocyte support. From the whole pool of follicles a woman is born with, only 0.1% of them will rise ovulation, whereas 99.9% will break down (in a process called follicular atresia). From birth, the ovaries of the human female contain a number of immature, primordial follicles.

What does reactive lymphoid follicles mean?

Background: Reactive lymphoid follicular hyperplasia is a benign proliferation of lymphoid follicles, which can develop wherever lymphoid tissue is present. We present the unique case of an RLFH that involved the radial nerve and presented as a peripheral nerve tumor.